Noubar Afeyan

PerSeptive Biosystems developed and manufactured an integrated system for the purification, analysis, and synthesis of bio-molecules, reducing the time and cost of drug discoveries. BVP’s Chris Gabrieli invested in the company’s second round in December 1989. PerSeptive was purchased by Perkin Elmer, Inc. (NYSE: PKI) in 1998, it is a part of Applied Biosystems (NYSE: ABI), a subsidiary of Applera, Perkin Elmer’s former biotechnology division

Applera Corp. manufactures medical instruments

Crystalplex Corp. operates a biochemistry and diagnostics laboratory that specializes in nanotechnology for the life sciences industry. Its proprietary technology, SapphireTM QDs provides a stable crystal design, flexible polymer matrix morphology, and meets environmentally responsible yet demanding performance requirements for high-end consumer electronics applications such as liquid crystal display televisions, displays, and high-CRI architectural lighting. The company was founded by Thomas A. Petzinge Jr. in 2004 and is headquartered in Pittsburgh, PA.

Epitome Biosystems was founded in 2004 by experts in the field of proteomic analysis. Backed by Flagship Ventures in Cambridge, MA, and with an outstanding Scientific Advisory Board, Epitome is set to become a world leader in multiplex protein analysis

Color Kinetics, Inc. designs and markets solid-state lighting systems. The company services include specifying, designing, installing, and operating of lighting systems. Its lighting systems include IntelliWhite, EssentialWhite Lighting Systems & Controllers, and accessories. The firm was co-founded by Ihor A. Lys and George G. Mueller in 1997 and is headquartered in Boston, MA.

Ensemble Therapeutics Corp. develops novel classes of therapeutics and bioassays for research and diagnostics. The firm focuses on the discovery and development of breakthrough small molecule therapies for patients with cancer and other serious diseases. The company was founded by Douglas G. Cole, Noubar B. Afeyan and David R. Liu in 2004 and is headquartered in Cambridge, MA.

Affinnova, Inc. is a global marketing technology, which provides sales solutions for large and mid-sized enterprises. The company was founded by Kamal M. Malek in 2000 and is headquartered in New York, NY.

DNIB Unwind, Inc. develops biopharmaceutical preparations. The company was founded by Omid C. Farokhzad and Robert S. Langer on May 19, 2006 and is headquartered in Los Angeles, CA.

Codon Devices, Inc. produces pharmaceuticals and biorefineries for the production of industrial chemicals and bio-energy. The firm designs and constructs biological components such as enzymes, biopharmaceuticals, and cell lines for improved function. Its customers include the biotechnology, pharmaceutical, and agriculture sectors. The company was founded by Noubar B. Afeyan, George Church, Drew Endy, Joseph M. Jacobson and Jay Keasling in 2004 and is headquartered in Cambridge, MA.

YourBio Health, Inc. develops health monitoring products. It is developing an array of products based on the company's proprietary TAP? (Touch Activated Phlebotomy) painless blood collection platform. The company was founded by Richard Rox Anderson, Joerg Lahann, Robert S. Langer Jr., Douglas A. Levinson and Samir Mitragotri in 2008 and is headquartered in Medford, MA.

Celera Group provides molecular diagnostics using proprietary genomics and proteomics discovery platforms to identify and validate novel diagnostic markers and to develop diagnostic products based on these markers. These diagnostic products are used to predict disease risk and optimize therapy selection, monitoring and patient outcome. The company was founded in May, 1998 and is located in Rockville, MD

Flagship Pioneering (Flagship Pioneering) is a venture capital firm founded in 1982 by Ed M Kania and Noubar B Afeyan. The firm is headquartered in Cambridge, Massachusetts.

Adnexus engages in the development of Adnectins biologics and medicines in the United States. The company was founded by Frank D. Lee on September 16, 2002 and is headquartered in Waltham, MA.

Helicos BioSciences Corp. is a life sciences company focused on innovative genetic analysis technologies and the monetization of those technologies and related intellectual property. The company was founded by Stanley N. Lapidus, Stephen D. Quake and Noubar B. Afeyan on May 9, 2003 and is headquartered in Cambridge, MA.

Selventa, Inc. develops new approaches for the understanding and treatment of diseases. It focuses on elucidating the complexity of biology for the development of safe and effective therapeutics and molecular diagnostics. The company was founded in 2002 by Keith O. Elliston and Noubar B. Afeyan and is headquartered in Cambridge, MA.

Adaptive Therapeutics, Inc. develops pharmaceutical products. It develops drugs for applications in anti-bacterial, fungal, viral, and cancer therapeutics. The company was founded in 2002 and is headquartered in San Diego, CA

Forum Mondial de L'Economie engages in the foremost political, business and cultural organizations to shape global, regional and industry agendas. The company was founded by Klaus Schwab in 1971 and is headquartered in Cologny, Switzerland.

Boston Symphony Orchestra Inc. performs symphony orchestra concerts. The organization performs concerts in Japan, China, South America, and Europe. The firm offers educational and training programs for professional musicians. The company was founded in 1881 by Henry Lee Higginson and is headquartered in Boston, MA.

The World Economic Forum USA, Inc. operates an organization for economic reforms. The non-profit company is based in New York, NY.

LS Dissolution, Inc. engages in the production of petroleum replacement products and industrial chemicals. It offers chemical and fuel products. The company was founded by George M. Church, Christopher Somerville, Noubar B. Afeyan and Jay D. Keasling in 2005 and is headquartered in South San Francisco, CA.

Joule Unlimited Technologies, Inc. produces renewable fuels and chemicals. It offers a technology platform for liquid fuel from the Sun. The company was founded by Noubar B. Afeyan in 2007 and is headquartered in Bedford, MA.

Armenian Assembly of America, Inc. promotes public awareness of Armenian Issues. It also assists in humanitarian and development programs in Armenia and Nagorno Karabakh, while strengthening the U.S.-Armenia and U.S.-Nagorno Karabakh relationships. The company was founded in 1972 and is headquartered in Washington, DC.

Sesen Bio, Inc. is a late-stage clinical company, which engages in the development of targeted fusion protein therapeutics. It offers Vicineum and Proxinium, which target tumor cell surface antigens that allow for rapid internalization into the targeted cancer cell and also have limited expression on normal cells. The company was founded by Reza Dana, K. Christopher Garcia, Gregory L. Verdine, Casey T. Weaver, and K. Dane Wittrup on February 25, 2008 and is headquartered in Cambridge, MA.

Ameriabank CJSC operates as a commercial bank. It offers corporate, investment and retail banking services. The firm's corporate banking services include financing, small and micro loans, deposits, account opening and services, cards and other financial services. Its investment banking services include mergers and acquisitions, corporate finance, foreign exchange transactions and brokerage. The firm's retail banking services include mortgage loans, car loans, consumer loans and savings account. The company was founded in 1910 and is headquartered in Yerevan, Armenia.

Theracrine, Inc. develops anti-metastatic drugs for cancer therapeutics. It provides scientific and technological services as well as research and design relating thereto. The company was founded by David A. Berry, Noubar B. Afeyan, Robert A. Weinberg, Joan Massagué and Douglas Hanahan in 2006 and is headquartered in Cambridge, MA.

Permeon Biologics, Inc. develops intracellular biotherapeutics platform to enhance drug delivery. Its intraphilin technology platform leverages research on remodeling the surfaces of proteins to permit cell penetration without losing their structure or activity; and enables functional proteins to replace or restore defective pathways inside cells that cause disease. The company was founded by Douglas G. Cole, David R. Liu, John W. Ripple, and Noubar B. Afeyan in 2008 and is headquartered in Cambridge, MA.

Essentient, Inc. develops transforming global nutrition. The company involves in research and development in biotechnology. The company was founded in 2008 and is headquartered in Cambridge, MA.

Midori USA, Inc. develops cellulosic technology for conversion of biomass to fuels. It offers biomass barrier technology that melts and digests biomass into sugars with a solid, recyclable catalyst. The company was founded by J. M. Geremia and Brian Baynes in 2008 and is headquartered in Cambridge, MA.

Celexion LLC develops platform technologies and products in the pharmaceutical, industrial, agricultural and life science research sectors. The company was founded by Brian Baynes in 2009 and is headquartered in Cambridge, MA.

AeroDesigns, Inc. manufactures novel devices and formulations that deliver natural nutrition through the act of breathing. The firm's novel nutritional delivery platform can be utilized for delivery of nutrients or pharmaceuticals directly to the mouth for ingestion, thus avoiding common safety concerns of delivering active molecules to the lungs. The company was founded by David Edwards and Thomas Hadfield in 2009 and is headquartered in Cambridge, MA.

WikiCell Designs, Inc. develops edible forms of food and beverage packaging services. The company was founded by Robert Connelly and David Allan Edwards in 2009 and is headquartered in Washington, DC.

Codiak BioSciences, Inc. engages in the development and manufacturing of exosomes. It engages in harnessing exosomes, therapeutic applications, diagnostic applications, and proprietary production. The firm develops engEx Platform, a proprietary and versatile exosome engineering and manufacturing platform, to expand upon the innate properties of exosomes to design novel exosome therapeutics. Codiak BioSciences was founded by Douglas E. William, Raghu Kalluri, and Eric S. Lander in 2015 and is headquartered in Cambridge, MA.

Rubius Therapeutics, Inc. engages in the development of red-cell therapeutic medicines. It provides medicine for cancer, autoimmune diseases, hemophilia, infectious and metabolic diseases. The company was founded on April 26, 2013 and is headquartered in Foxboro, MA.

Epiva Biosciences, Inc. develops immunobiotic therapeutics. The company is headquartered in Cambridge, MA.

CiBO Technologies, Inc. is a science-driven software company which engage sin the modelling and simulation of agricultural ecosystems. The firm offers CIBO and CIBO Plus software products. The company was founded by Ignacio Bemposta Martinez and Bruno Basso in 2015 and is headquartered in Cambridge, MA.

Ohana Biosciences, Inc. operates early stage biotechnology firm. The company is headquartered in Cambridge, MA.

Cygnal Therapeutics, Inc. develops drugs for cancer, immunological diseases and regenerative processes. The company was founded by Noubar Afeyan, Avak Kahvejian and Jordi Mata-Fink in 2017 and is headquartered in Cambridge, MA.

Cogen Immune Medicine, Inc. develops immune modulation therapeutics which control immune system. Its platform includes therapeutics, vaccines, clinical decision making, and immune health. The company was founded by Noubar B. Afeyan in 2017 and is headquartered in Cambridge, MA.

Cobalt Biomedicine, Inc. engages in the development of therapeutic based drugs. The company was founded in 2017 and is headquartered in Cambridge, MA.

Ring Therapeutics, Inc. engages in the development of a gene therapy platform. Its Anellovector platform provides tissue specifities benefitting from the inherent diversity of tropism afforded by the commensal virome. The company was founded in 2000 and is headquartered in Cambridge, MA.

Repertoire Immune Medicines, Inc. operates as a clinical-stage biotechnology company. It focuses on the immune system to prevent, treat, and cure cancer, autoimmune disorders, and infectious diseases. The company was founded by Noubar Afeyan and is headquartered in Cambridge, MA.

Invaio Sciences, Inc. operates as multi-platform technology company. The firm develops multi-platform technology company that unlocks the potential of planet's interdependent natural systems to solve pressing agriculture, nutrition and environmental challenges. The company was founded in 2018 and is headquartered in Cambridge, MA.

Indigo Ag, Inc. provides microbial solutions. The company was founded by Noubar Afeyan, David A. Berry, and Geoffrey von Maltzahn in 2013 and is headquartered in Charlestown, MA.

Tessera Therapeutics, Inc. engages in science company. It offers scientists and doctors the ability to write and rewrite small and large therapeutic messages into the genome, thereby curing diseases at their source. The company is headquartered in Cambridge, MA.

Cellarity Inc. engages in the operation of platform to design medicines targeting the full cellular and molecular complexity of disease. The company was founded by Avak Kahvejian, James J. Collins, Noubar Afeyan, and Nicholas Plugis in 2017 and is headquartered in Cambridge, MA.

Generate Biomedicines, Inc. is a drug generation company that has developed a machine learning-powered multimodality generative biology platform capable of generating new drugs on demand across a wide range of biologic modalities. Generate Biomedicines is based in Somerville, MA. The platform seamlessly integrates computational and wet lab capabilities, improving the speed at which targets and therapeutics are identified and validated, the specificity of target engagement by generated proteins, and the cost of identifying and developing clinical candidates. The company's platform represents a potentially fundamental shift in what's possible in the field of therapeutic development, addressing key challenges of drug discovery and drastically expanding the available search space for novel biomedicines. The company was founded in 2018 by Poorya Hosseini, Molly Gibson, Geoffrey von Maltzahn, Avak Kahvejian, Gevorg Grigoryan. Michael T. Nally has been the CEO of the company since 2018.

Part of Sonata Therapeutics, Inc., Inzen Therapeutics, Inc. is discovering and developing a novel class of medicines based on thanokine biology. The private company is based in Cambridge, MA. Thanokine biology offers the potential for unprecedented approaches to prevent and treat cancer, fibrotic disorders, immune-inflammatory disorders, metabolic disorders, and degenerative diseases. Inzen's thanokine product platform applies advances in mass spectrometry and machine learning, novel probes, unique assays, genetic and chemical biological technologies to characterize thanokine biology at scale and create drug candidates. Inzen Therapeutics harnesses signals of the cellular microenvironment to treat serious diseases. The company was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

Alltrna is a biotech company that uses AI/ML tools to learn the language of tRNA and develop programmable molecules with therapeutic potential. Alltrna was founded in 2018 by Flagship Pioneering and is based in Cambridge, MA. The company aims to correct diseases by advancing a single tRNA medicine to treat a wide range of diseases with the same underlying genetic mutation. The company's CEOs are Michelle C. Werner and Lovisa Afzelius.

Laronde Inc. is a company that aims to advance eRNA-based therapeutics through their powerful new platform called endless RNA (eRNA™). The company is based in Cambridge, MA and was founded by Noubar B. Afeyan. This platform can be programmed to make any therapeutic protein inside the body, making it the most versatile RNA platform for life-changing medicines.

Profound Therapeutics is a company that is focused on discovering new medicines by expanding the human proteome. The company is based in Cambridge, MA. The company uses their platform, Profoundry, to identify and validate proteins and understand their therapeutic potential. This results in a growing database of novel proteins and their roles in health and disease. The company was founded in 2020 by Avak Kahvejian, who has been the CEO since then.

Montai Health, Inc. is a company that is using its pioneering AI-powered Conecta™ platform to develop Anthromolecule™ medicines that will treat and preempt chronic diseases to improve health outcomes for the 2 billion people worldwide living with these diseases. The company is based in Cambridge, MA. Montai Health is unlocking the potential of Anthromolecule™ chemistry with its pioneering AI-powered Conecta™ platform to develop breakthrough small-molecule medicines that will treat and preempt chronic diseases to improve health outcomes for the two billion people worldwide living with these diseases. The company was founded by Hok Hei Tam, Michael Wong, David Kolesky, Mary Margaret Hastings Georgiadis. Mary Margaret Hastings Georgiadis has been the CEO since incorporation.

Ampersand Biomedicines is an American company that designs programmable medicines that work precisely where needed in the body and nowhere else. The company's computationally powered platform identifies ideal addresses for drug localization and informs the design of and-body™ therapeutics that have the optimal therapeutic effect. The result is smarter biologic medicines that target the site of disease without affecting healthy tissue or cells. Ampersand is enabling potent mechanisms to treat disease by creating and programming therapeutics that are more efficacious, without compromising on safety or tolerability. The company was founded in 2020 at Flagship Labs, a unit of Flagship Pioneering. Jason Gardner has been the CEO of the company since 2023.

Kintai Therapeutics, Inc. engages in discovering and development of precision enteric medicine. It offers discovery platform, enteric biology and analytics, and precision enteric medicines. The company was founded in 2016 and is headquartered in Cambridge, MA.

MIT Solve (MIT Solve) is a venture capital firm. The firm is headquartered in Cambridge, Massachusetts.