James R. Appleman

Polaris Partners is an Independent Venture Capital firm founded in 1996 by Stephen D. Arnold, Jonathan A. Flint and Terrance G. McGuire. Polaris Partners is headquartered in Waltham.

Oberland Capital Management LLC (Oberland Capital) is a private equity firm founded in 2013 by Jean-Pierre Naegeli and Andrew Rubinstein. The firm is headquartered in New York.

Valence Life Sciences LLC (Valence Life Sciences) is an venture capital firm founded in 2012 by Rachel Anne Leheny and Eric Wayne Roberts. The firm is headquartered in New York.

Seaview Securities LLC provides investment banking services focused on the life sciences industry. The firm's services include private placements, mergers & acquisitions, financial and business strategy advisory, and underwriting services. The company was founded in January 2002 by Russell L. Pollack and Joseph P. Dougherty and is headquartered in New York, NY.

Gemin X Pharmaceuticals US Inc. is engaged in the development of cancer therapeutics. It offers mimetic and telomere capping programs, as well as screening, medicinal chemistry, and preclinical development services. The company was founded by Gordon C. Shore in 1998 and is headquartered in Malvern, PA.

Microban International Ltd. provides built-in antimicrobial product protection and antifungal solutions. The firm serves consumer, industrial and medical product to avoid the growth of microbes, such as bacteria, mold and mildew that can cause stains, odors and deterioration of a product. It has locations in North America, Latin America, Europe and Asia. The company was founded in 1984 and is headquartered in Huntersville, NC.

Founded in 1991 by Philip Paul, Paul Capital Partners LP is a private equity firm located in San Francisco with additional offices in New York City, Hong Kong, London, Paris and São Paulo.

Satellite Biosciences, Inc. is a company based in Cambridge, MA that is focused on developing innovative regenerative medicine solutions to tackle some of the most challenging diseases. The company's mission is to create a new category of regenerative medicine called Tissue Therapeutics. The company was founded by Sangeeta N. Bhatia, Christopher S. Chen, and Arnav Chhabra. David Lennon has been the CEO of the company since 2021.

Matter Neuroscience is an American company that develops mobile applications for neurological reward systems. The private company was founded by Benjamin Goldhirsh and Axel Bouchon, with Axel Bouchon serving as the CEO since incorporation.

Soufflé Therapeutics, Inc. engages in pharmaceutical research and development services. The company is based in Newton, MA. The CEO of the company is Amir H. Nashat.

Alioth, Inc. operates as a hiring success platform. The private company is based in Spicewood, TX. The company was founded in 2018 by Amir H. Nashat, Kenneth A. DiPietro, Janet Stafford, James Russell Rueff. Janet Stafford has been the CEO since 2018.

Caxton Alternative Management LP (do-business-as CAM Capital) is a single-family office which was founded in 2012 by Bruce Kovner following his retirement from Caxton Associates, the macro hedge fund he founded and managed from 1983 to 2011. Headquartered in New York City, CAM Capital manages assets exclusively for entities related to Mr. Kovner and its senior employees.

Agouron Pharmaceuticals LLC develops and distributes therapeutic products. It provides therapeutic products which are used in the treatment of cardiovascular disease, central nervous system diseases and disorders, neurological disorders, inflammatory diseases, respiratory diseases, infectious diseases, immunological disorders, pharmaceutical preparations and other diseases. The company was founded in 1984 and is headquartered in San Diego, CA.

Anavo Therapeutics BV is a Dutch company that specializes in developing first-in-class therapeutic programs for several indications in oncology. The company is based in Leiden, Netherlands. The company has attracted world-leading scientific expertise in phosphatase-driven disease biology and drug discovery to unlock the full potential of phosphatase-targeted allosteric modulators. Anavo is the first company to systematically drug phosphatases, a rich target space previously considered undruggable for decades. Anavo is backed by blue-chip investors m ventures, inkef capital, taiho ventures, mrl ventures fund, and bioqube ventures. The company was founded by Claus Schalper, Birgit Zech, Gerhard Müller. Birgit Zech has been the CEO since incorporation.

Impact Biomedicines, Inc. engages in the development of cancer treatments. It engages in the development of fedratinib, a potent and selective oral molecule JAK2 kinase inhibitor for the treatment of myelofibrosis and polycythemia vera. The company was founded by John Hood, Catriona Jamieson and Raghu Saripalli in 2016 and is headquartered in San Diego, CA.

Paratus Sciences Corp. is an American company that focuses on unlocking the secrets of bat biology. The company's main goal is to elucidate novel insights and identify new therapeutic targets. The company was founded by Thomas Zwaka, Richard Young, Paul Matsudaira. The CEO is Amir H. Nashat.

Avenge Bio, Inc. is an oncology-focused biotechnology company based in the United States. The American company develops cell-based immunotherapeutic products for the treatment of solid tumors using its proprietary Lococyte™ platform. The platform delivers engineered cells to the local tumor environment, generating high concentrations of immune effector molecules in proximity to the tumor, which initiates a robust, local, and durable systemic immune response while avoiding toxicities associated with systemic immunotherapies. Avenge's most advanced product candidate, AVB-001, produces native IL-2 immunotherapy and is initially being studied in metastatic peritoneal cancers such as ovarian cancer. The company has additional pipeline candidates for the treatment of a wide range of cancers, including pancreatic, lung, and breast cancers. Avenge was founded in 2019 by Paul Kevin Wotton and Michael Thomas Heffernan, with Heffernan serving as CEO since incorporation.

Palvella Therapeutics, Inc. operates as a rare disease biopharmaceutical company. It develops and commercializes pathogenetically targeted therapies for rare genodermatoses with no approved treatments. Its products include QTORIN, PTX-022, PTX-367, and PTX-014. The company was founded by Wesley H. Kaupinen in 2015 and is headquartered in Wayne, PA.

Antios Therapeutics, Inc. operates as a biopharmaceutical company devoted to developing therapies for viral diseases. The company was founded by Abel De La Rosa, Doug Mayers and Idean Marvasty on October 30, 2018 and is headquartered in Atlanta, GA.

Molecular Templates OpCo, Inc. provides medical services. The company is headquartered in Austin, TX.

Pervasis Therapeutics, Inc. is a clinical stage company developing a broad portfolio of biologically active therapeutics. The company was founded by Robert S. Langer Jr. and Helen Marie Nugent in 2004 and is headquartered in Waltham, MA.

Part of Quintiles Transnational Corp., Quintiles Biosciences, Inc. is a bioanalytical laboratory. The company is based in Ithaca, NY.

Adnexus engages in the development of Adnectins biologics and medicines in the United States. The company was founded by Frank D. Lee on September 16, 2002 and is headquartered in Waltham, MA.